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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50389186'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50389186(CHEMBL2062803 | US8501936, 4)
Affinity DataIC50:  17nMAssay Description:Inhibition of human JAK3 expressed in baculovirus using biotinyl-amino-hexanoyl-EQEDEPEGDYFEWLE-amide as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50389186(CHEMBL2062803 | US8501936, 4)
Affinity DataIC50:  22.5nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In DepthDetails US Patent