Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM340070'
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM340070((S)-4-(8-amino-3-(1-(2- chloropyrimidine-4- carbon...)
Affinity DataEC50: >1.00E+3nMAssay Description:Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM340070((S)-4-(8-amino-3-(1-(2- chloropyrimidine-4- carbon...)
Affinity DataEC50: >1.00E+3nMAssay Description:Lck enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lck enzyme (M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM340070((S)-4-(8-amino-3-(1-(2- chloropyrimidine-4- carbon...)
Affinity DataEC50: >1.00E+3nMAssay Description:Lck enzyme (Millipore catalog #14-442), is diluted to 0.4 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.05% NaN3, 1 mM DTT, 2 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent