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Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50305117'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50305117
PNG
(7-(2-morpholinoethoxy)-2-(4-phenoxyphenyl)-9,10-di...)
Show SMILES NC(=O)c1c2Nc3ccc(OCCN4CCOCC4)cc3CCn2nc1-c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C30H31N5O4/c31-29(36)27-28(21-6-8-24(9-7-21)39-23-4-2-1-3-5-23)33-35-13-12-22-20-25(10-11-26(22)32-30(27)35)38-19-16-34-14-17-37-18-15-34/h1-11,20,32H,12-19H2,(H2,31,36)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.560n/an/an/an/an/an/a



Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human LCK by scintillation counting


Bioorg Med Chem Lett 20: 112-6 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.013
BindingDB Entry DOI: 10.7270/Q22Z15NV
More data for this
Ligand-Target Pair