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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lyn' and Ligand = 'BDBM340137'
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM340137(US10239883, Example 26 | US10934296, Example 26 | ...)
Affinity DataEC50: >1.00E+3nMAssay Description:Lyn enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lyn enzyme (M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM340137(US10239883, Example 26 | US10934296, Example 26 | ...)
Affinity DataEC50: >1.00E+3nMAssay Description:Lyn enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.Lyn enzyme (M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM340137(US10239883, Example 26 | US10934296, Example 26 | ...)
Affinity DataEC50: >1.00E+3nMAssay Description:Lyn enzyme (Millipore catalog #14-510), is diluted to 250 mU/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.05% NaN3, 1 mM DTT, 2 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent