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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM336245'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336245
PNG
(US9744172, Compound UNC00000483A)
Show SMILES CCOc1ccc(cc1)-c1ccc(cc1)-c1nn(CC2CCC(N)CC2)c2nc(NC)ncc12
Show InChI InChI=1S/C27H32N6O/c1-3-34-23-14-10-20(11-15-23)19-6-8-21(9-7-19)25-24-16-30-27(29-2)31-26(24)33(32-25)17-18-4-12-22(28)13-5-18/h6-11,14-16,18,22H,3-5,12-13,17,28H2,1-2H3,(H,29,30,31)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair