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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM336275'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336275
PNG
(US9744172, Compound UNC606A)
Show SMILES CCCCNc1ncc2c(nn(CC3CCNCC3)c2n1)-c1ccc(nc1)N1CCNCC1
Show InChI InChI=1S/C24H35N9/c1-2-3-8-27-24-29-16-20-22(19-4-5-21(28-15-19)32-13-11-26-12-14-32)31-33(23(20)30-24)17-18-6-9-25-10-7-18/h4-5,15-16,18,25-26H,2-3,6-14,17H2,1H3,(H,27,29,30)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair