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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM336286'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336286
PNG
(US9744172, Compound UNC783A)
Show SMILES CCCCNc1ncc2c(nn(CC3CC[C@@H](CC3)NS(C)(=O)=O)c2n1)-c1ccc(F)cc1
Show InChI InChI=1S/C23H31FN6O2S/c1-3-4-13-25-23-26-14-20-21(17-7-9-18(24)10-8-17)28-30(22(20)27-23)15-16-5-11-19(12-6-16)29-33(2,31)32/h7-10,14,16,19,29H,3-6,11-13,15H2,1-2H3,(H,25,26,27)/t16?,19-
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair