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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM336324'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336324
PNG
(US9744172, Compound UNC00000464A)
Show SMILES CCCCCCCNc1ncc2c(nn(CC3CCC(N)CC3)c2n1)-c1ccccc1
Show InChI InChI=1S/C25H36N6/c1-2-3-4-5-9-16-27-25-28-17-22-23(20-10-7-6-8-11-20)30-31(24(22)29-25)18-19-12-14-21(26)15-13-19/h6-8,10-11,17,19,21H,2-5,9,12-16,18,26H2,1H3,(H,27,28,29)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair