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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM336357'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336357
PNG
(US9744172, Compound UNC707A)
Show SMILES CCCNc1ncc2c(nn(CC3CCN(CC3)C(=O)OC(C)(C)C)c2n1)-c1ccccc1OC
Show InChI InChI=1S/C26H36N6O3/c1-6-13-27-24-28-16-20-22(19-9-7-8-10-21(19)34-5)30-32(23(20)29-24)17-18-11-14-31(15-12-18)25(33)35-26(2,3)4/h7-10,16,18H,6,11-15,17H2,1-5H3,(H,27,28,29)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 2.00E+4n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair