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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM336398'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336398
PNG
(US9744172, Compound UNC910A)
Show SMILES CCCCNc1ncc2c(nn(CCCN3CCOCC3)c2n1)-c1ccc(cc1)S(=O)(=O)NC
Show InChI InChI=1S/C23H33N7O3S/c1-3-4-10-25-23-26-17-20-21(18-6-8-19(9-7-18)34(31,32)24-2)28-30(22(20)27-23)12-5-11-29-13-15-33-16-14-29/h6-9,17,24H,3-5,10-16H2,1-2H3,(H,25,26,27)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair