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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM336399'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336399
PNG
(US9744172, Compound UNC911A)
Show SMILES CCCCNc1ncc2c(nn(CCC3CC[C@H](O)CC3)c2n1)-c1ccc(cc1)S(=O)(=O)NC
Show InChI InChI=1S/C24H34N6O3S/c1-3-4-14-26-24-27-16-21-22(18-7-11-20(12-8-18)34(32,33)25-2)29-30(23(21)28-24)15-13-17-5-9-19(31)10-6-17/h7-8,11-12,16-17,19,25,31H,3-6,9-10,13-15H2,1-2H3,(H,26,27,28)/t17?,19-
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair