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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM336428'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM336428
PNG
(US9744172, Compound UNC1182A)
Show SMILES CCCCNc1ncc2c(nn(CC3CC[C@H](N)CC3)c2n1)-c1ccc(cc1)N1CCOCC1=O
Show InChI InChI=1S/C26H35N7O2/c1-2-3-12-28-26-29-15-22-24(19-6-10-21(11-7-19)32-13-14-35-17-23(32)34)31-33(25(22)30-26)16-18-4-8-20(27)9-5-18/h6-7,10-11,15,18,20H,2-5,8-9,12-14,16-17,27H2,1H3,(H,28,29,30)/t18?,20-
PDB
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PC cid
PC sid
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US Patent
n/an/a<10n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
The ectopic expression of Mer receptor tyrosine kinase (Mer) has been identified as a tumor cell survival gene product in Acute Lymphoblastic Leukemi...


US Patent US9744172 (2017)

More data for this
Ligand-Target Pair