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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM50384591'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM50384591
PNG
(CHEMBL2036627)
Show SMILES CNc1ncc2c(nn(C[C@@H]3CC[C@H](O)CC3)c2n1)-c1ccccc1
Show InChI InChI=1S/C19H23N5O/c1-20-19-21-11-16-17(14-5-3-2-4-6-14)23-24(18(16)22-19)12-13-7-9-15(25)10-8-13/h2-6,11,13,15,25H,7-10,12H2,1H3,(H,20,21,22)/t13-,15+
PDB
MMDB

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Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Mer expressed in Escherichia coli BL21 (DE3) cells using EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluid capillary electr...


ACS Med Chem Lett 3: 129-134 (2012)


Article DOI: 10.1021/ml200239k
BindingDB Entry DOI: 10.7270/Q2F76DMC
More data for this
Ligand-Target Pair