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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM50384595'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))
BDBM50384595
PNG
(CHEMBL2036631)
Show SMILES CNc1ncc2c(nn(CC3CCC(N)CC3)c2n1)-c1cccc(OC)c1
Show InChI InChI=1S/C20H26N6O/c1-22-20-23-11-17-18(14-4-3-5-16(10-14)27-2)25-26(19(17)24-20)12-13-6-8-15(21)9-7-13/h3-5,10-11,13,15H,6-9,12,21H2,1-2H3,(H,22,23,24)
PDB
MMDB

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PC cid
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Similars

Article
PubMed
n/an/a 120n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Mer expressed in Escherichia coli BL21 (DE3) cells using EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluid capillary electr...


ACS Med Chem Lett 3: 129-134 (2012)


Article DOI: 10.1021/ml200239k
BindingDB Entry DOI: 10.7270/Q2F76DMC
More data for this
Ligand-Target Pair