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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM140389'
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM140389(US10947243, Example 114 | US8912173, 114 | US99147...)
Affinity DataIC50:  0.200nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie—Dept. of Biochemistry) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM140389(US10947243, Example 114 | US8912173, 114 | US99147...)
Affinity DataIC50:  0.5nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent