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Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM189859'
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM189859(US9670196, 1.4 (R or S)-5-hydroxy-5-(5- (6-((2-met...)
Affinity DataIC50:  5.50nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent