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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM206127'
Target
Tyrosine-protein kinase SYK
(Homo sapiens (Human))
Roche Palo Alto
US Patent
Ligand
BDBM206127
(US9255110, 40)
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Affinity Data
IC50: 500nM
pH: 7.2 T: 2°C
Assay Description:
SYK activity is measured by phosphorylation of a peptide substrate (Biotin-EPEGDYEEVLE) with [gamma-33P] ATP. The enzyme reaction was conducted at 20...
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Ligand Info
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