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Found 4 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM255476'
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
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US Patent
LigandPNGBDBM255476(US10125100, Example 1 | US10392346, Example 1 | US...)
Affinity DataIC50:  5nMAssay Description:The inhibitory activities of the compound of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that des...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
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US Patent
LigandPNGBDBM255476(US10125100, Example 1 | US10392346, Example 1 | US...)
Affinity DataIC50:  5nMAssay Description:c-Src and Syk: The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
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US Patent
LigandPNGBDBM255476(US10125100, Example 1 | US10392346, Example 1 | US...)
Affinity DataKd:  7.10nMAssay Description:c-Src and Syk: The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM255476(US10125100, Example 1 | US10392346, Example 1 | US...)
Affinity DataKd:  7.10nMAssay Description:Kinase enzyme binding activities of the compound disclosed herein may be determined using a proprietary assay which measures active site-directed com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent