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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM255500'
Target
Tyrosine-protein kinase SYK
(Homo sapiens (Human))
Rigel Pharmaceuticals
US Patent
Ligand
BDBM255500
(US9499493, R945144)
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Affinity Data
IC50: 383nM
pH: 7.4 T: 2°C
Assay Description:
Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...
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