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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM334327'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM334327
PNG
(3-(4-((4-(3-(3-Isopropyl-1-(p-tolyl)-1H-pyrazol-5-...)
Show SMILES CC(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4cccc(OS(C)(=O)=O)c4)n3)c3ccccc23)n(n1)-c1ccc(C)cc1
Show InChI InChI=1S/C35H33N7O5S/c1-22(2)30-21-32(42(41-30)25-14-12-23(3)13-15-25)39-35(43)38-29-16-17-31(28-11-6-5-10-27(28)29)46-33-18-19-36-34(40-33)37-24-8-7-9-26(20-24)47-48(4,44)45/h5-22H,1-4H3,(H,36,37,40)(H2,38,39,43)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>622n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...


US Patent US9732063 (2017)

More data for this
Ligand-Target Pair