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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM334338'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM334338
PNG
(1-(4-((2-((3-(2-Hydroxyethyl)thio)-5-methoxyphenyl...)
Show SMILES COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4ccc(C)cc4)C(C)C)c4ccccc34)n2)cc(SCCO)c1
Show InChI InChI=1S/C37H37N7O4S/c1-23(2)32-22-34(44(43-32)26-11-9-24(3)10-12-26)41-37(46)40-31-13-14-33(30-8-6-5-7-29(30)31)48-35-15-16-38-36(42-35)39-25-19-27(47-4)21-28(20-25)49-18-17-45/h5-16,19-23,45H,17-18H2,1-4H3,(H,38,39,42)(H2,40,41,46)
PDB
MMDB

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PC cid
PC sid
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Article
US Patent
n/an/a 134n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...


US Patent US9732063 (2017)


Article DOI: 10.1021/jm060978s
More data for this
Ligand-Target Pair