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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM334377'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM334377
PNG
(1-(3-(tert-Butyl)-1-(6-methoxypyridin-3-yl)-1H-pyr...)
Show SMILES COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4ccc(OC)nc4)C(C)(C)C)c4ccccc34)n2)cc(c1)S(=O)(=O)C1CC1
Show InChI InChI=1S/C38H38N8O6S/c1-38(2,3)32-21-33(46(45-32)24-10-15-34(51-5)40-22-24)43-37(47)42-30-13-14-31(29-9-7-6-8-28(29)30)52-35-16-17-39-36(44-35)41-23-18-25(50-4)20-27(19-23)53(48,49)26-11-12-26/h6-10,13-22,26H,11-12H2,1-5H3,(H,39,41,44)(H2,42,43,47)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 120n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
c-Src and Syk Enzyme InhibitionThe inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a...


US Patent US9732063 (2017)

More data for this
Ligand-Target Pair