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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM339996'
Target
Tyrosine-protein kinase SYK
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM339996
(5-(((3R,4R)-3-aminotetrahydro-2H-pyran-4-yl)amino)...)
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Affinity Data
IC50: 3nM
Assay Description:
A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...
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