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Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 11' and Ligand = 'BDBM24520'
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Aristotle University

LigandPNGBDBM24520((2E,5E)-5-[(3-chlorophenyl)methylidene]-2-(1,3-thi...)
Affinity DataKi:  1.09E+6nM ΔG°:  -16.9kJ/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed