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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 22' and Ligand = 'BDBM50335864'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein phosphatase non-receptor type 22


(Homo sapiens (Human))
BDBM50335864
PNG
(3-(1-(4-(4-bromonaphthalen-1-ylamino)-4-oxobutyl)-...)
Show SMILES Cc1ccc(cc1)-c1oc2cc(O)c(cc2c1-c1cn(CCCC(=O)Nc2ccc(Br)c3ccccc23)nn1)C(O)=O
Show InChI InChI=1S/C32H25BrN4O5/c1-18-8-10-19(11-9-18)31-30(23-15-22(32(40)41)27(38)16-28(23)42-31)26-17-37(36-35-26)14-4-7-29(39)34-25-13-12-24(33)20-5-2-3-6-21(20)25/h2-3,5-6,8-13,15-17,38H,4,7,14H2,1H3,(H,34,39)(H,40,41)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 270n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of recombinant LyP assessed as hydrolysis of DiFMUP


J Med Chem 54: 562-71 (2011)


Article DOI: 10.1021/jm101004d
BindingDB Entry DOI: 10.7270/Q2N016T4
More data for this
Ligand-Target Pair