Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosyl-DNA phosphodiesterase 1' and Ligand = 'BDBM50008923'
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-[32P]-labeled single stranded DNA containing a 3'-phosphotyrosine as substrate after 15 mins...More data for this Ligand-Target Pair
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) assessed as decrease in hydrolysis of phosphodiester linkage between tyrosine residue and the 3' end ...More data for this Ligand-Target Pair