BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'UTS2R' and Ligand = 'BDBM50089671'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
UTS2R


(RAT)
BDBM50089671
PNG
(CHEMBL3577300)
Show SMILES NCCC[C@@H]1N=C(c2[nH]c(cc2N(CCc2ccc(O)cc2)C1=O)C(O)=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1/C31H30N4O4/c32-17-4-7-25-30(37)35(18-16-20-8-14-24(36)15-9-20)27-19-26(31(38)39)34-29(27)28(33-25)23-12-10-22(11-13-23)21-5-2-1-3-6-21/h1-3,5-6,8-15,19,25,34,36H,4,7,16-18,32H2,(H,38,39)/t25-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 12n/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Modulation of urotensin-2 receptor in Sprague-Dawley rat thoracic aortic ring assessed as human urotensin-2 EC50 for induction of aortic ring contrac...


J Med Chem 58: 4624-37 (2015)

More data for this
Ligand-Target Pair
UTS2R


(RAT)
BDBM50089671
PNG
(CHEMBL3577300)
Show SMILES NCCC[C@@H]1N=C(c2[nH]c(cc2N(CCc2ccc(O)cc2)C1=O)C(O)=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1/C31H30N4O4/c32-17-4-7-25-30(37)35(18-16-20-8-14-24(36)15-9-20)27-19-26(31(38)39)34-29(27)28(33-25)23-12-10-22(11-13-23)21-5-2-1-3-6-21/h1-3,5-6,8-15,19,25,34,36H,4,7,16-18,32H2,(H,38,39)/t25-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 23n/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Modulation of urotensin-2 receptor in Sprague-Dawley rat thoracic aortic ring assessed as urotensin-2 related peptide pEC50 for induction of aortic r...


J Med Chem 58: 4624-37 (2015)

More data for this
Ligand-Target Pair
UTS2R


(RAT)
BDBM50089671
PNG
(CHEMBL3577300)
Show SMILES NCCC[C@@H]1N=C(c2[nH]c(cc2N(CCc2ccc(O)cc2)C1=O)C(O)=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1/C31H30N4O4/c32-17-4-7-25-30(37)35(18-16-20-8-14-24(36)15-9-20)27-19-26(31(38)39)34-29(27)28(33-25)23-12-10-22(11-13-23)21-5-2-1-3-6-21/h1-3,5-6,8-15,19,25,34,36H,4,7,16-18,32H2,(H,38,39)/t25-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 12n/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Modulation of urotensin-2 receptor in Sprague-Dawley rat thoracic aortic ring assessed as human urotensin-2 pEC50 for induction of aortic ring contra...


J Med Chem 58: 4624-37 (2015)

More data for this
Ligand-Target Pair
UTS2R


(RAT)
BDBM50089671
PNG
(CHEMBL3577300)
Show SMILES NCCC[C@@H]1N=C(c2[nH]c(cc2N(CCc2ccc(O)cc2)C1=O)C(O)=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1/C31H30N4O4/c32-17-4-7-25-30(37)35(18-16-20-8-14-24(36)15-9-20)27-19-26(31(38)39)34-29(27)28(33-25)23-12-10-22(11-13-23)21-5-2-1-3-6-21/h1-3,5-6,8-15,19,25,34,36H,4,7,16-18,32H2,(H,38,39)/t25-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 23n/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Modulation of urotensin-2 receptor in Sprague-Dawley rat thoracic aortic ring assessed as urotensin-2 related peptide EC50 for induction of aortic ri...


J Med Chem 58: 4624-37 (2015)

More data for this
Ligand-Target Pair