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Found 3 Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 30' and Ligand = 'BDBM445169'
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Mitobridge, Inc. (An Astellas)

Curated by ChEMBL
LigandPNGBDBM445169((S)-1-cyano-N-(4-(3- cyanophenyl)thiazol-2-yl)- N-...)
Affinity DataIC50: <100nMAssay Description:Inhibition of USP30 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Mitobridge, Inc. (An Astellas)

Curated by ChEMBL
LigandPNGBDBM445169((S)-1-cyano-N-(4-(3- cyanophenyl)thiazol-2-yl)- N-...)
Affinity DataIC50:  550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Mitobridge, Inc. (An Astellas)

Curated by ChEMBL
LigandPNGBDBM445169((S)-1-cyano-N-(4-(3- cyanophenyl)thiazol-2-yl)- N-...)
Affinity DataIC50:  550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent