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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ubiquitin-like modifier-activating enzyme 1' and Ligand = 'BDBM329839'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ubiquitin-like modifier-activating enzyme 1


(Homo sapiens (Human))
BDBM329839
PNG
((rac)-(1R,2R,3S,4R)-4-(2-(3-cyclopentenylphenyl)py...)
Show SMILES NS(=O)(=O)OC[C@H]1C[C@@H](Nc2ccnc3cc(nn23)-c2cccc(c2)C2=CCCC2)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C23H27N5O5S/c24-34(31,32)33-13-17-11-19(23(30)22(17)29)26-20-8-9-25-21-12-18(27-28(20)21)16-7-3-6-15(10-16)14-4-1-2-5-14/h3-4,6-10,12,17,19,22-23,26,29-30H,1-2,5,11,13H2,(H2,24,31,32)/t17-,19-,22-,23+/m1/s1
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

US Patent


Assay Description
The UAE enzymatic reaction totals 50 μL and contains 50 mmol HEPES (pH 7.5), 0.05% BSA, 2.5 mM MgCl2, 0.1 uM ATP, 8 nM GST-Ubc-2, 35 nM flag-ubi...


US Patent US10202389 (2019)

More data for this
Ligand-Target Pair