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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ubiquitin-like modifier-activating enzyme 1' and Ligand = 'BDBM329852'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ubiquitin-like modifier-activating enzyme 1


(Homo sapiens (Human))
BDBM329852
PNG
((rac)-((1R,2R,3S,4R)-2,3-Dihydroxy-4-((2-(5-(trifl...)
Show SMILES NS(=O)(=O)OC[C@H]1C[C@@H](Nc2ccnc3cc(nn23)-c2ccc(s2)C(F)(F)F)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C17H18F3N5O5S2/c18-17(19,20)12-2-1-11(31-12)9-6-14-22-4-3-13(25(14)24-9)23-10-5-8(15(26)16(10)27)7-30-32(21,28)29/h1-4,6,8,10,15-16,23,26-27H,5,7H2,(H2,21,28,29)/t8-,10-,15-,16+/m1/s1
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

US Patent


Assay Description
The UAE enzymatic reaction totals 50 μL and contains 50 mmol HEPES (pH 7.5), 0.05% BSA, 2.5 mM MgCl2, 0.1 uM ATP, 8 nM GST-Ubc-2, 35 nM flag-ubi...


US Patent US10202389 (2019)

More data for this
Ligand-Target Pair