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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ubiquitin-like modifier-activating enzyme 1' and Ligand = 'BDBM329869'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ubiquitin-like modifier-activating enzyme 1


(Homo sapiens (Human))
BDBM329869
PNG
((rac)-((1R,2R,3S,4R)-2,3-dihydroxy-4-(2-(3-(piperi...)
Show SMILES NS(=O)(=O)OC[C@H]1C[C@@H](Nc2ccnc3cc(nn23)-c2cccc(c2)N2CCCCC2)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C23H30N6O5S/c24-35(32,33)34-14-16-12-19(23(31)22(16)30)26-20-7-8-25-21-13-18(27-29(20)21)15-5-4-6-17(11-15)28-9-2-1-3-10-28/h4-8,11,13,16,19,22-23,26,30-31H,1-3,9-10,12,14H2,(H2,24,32,33)/t16-,19-,22-,23+/m1/s1
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

US Patent


Assay Description
The UAE enzymatic reaction totals 50 μL and contains 50 mmol HEPES (pH 7.5), 0.05% BSA, 2.5 mM MgCl2, 0.1 uM ATP, 8 nM GST-Ubc-2, 35 nM flag-ubi...


US Patent US10202389 (2019)

More data for this
Ligand-Target Pair