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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ubiquitin-like modifier-activating enzyme 1' and Ligand = 'BDBM329891'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ubiquitin-like modifier-activating enzyme 1


(Homo sapiens (Human))
BDBM329891
PNG
((rac)-rel-5-[7-({(1R,2S,3R,4R)-2,3-dihydroxy-4- | ...)
Show SMILES NS(=O)(=O)OC[C@H]1C[C@@H](Nc2ccnc3cc(nn23)-c2cccc3cc(ccc23)C(O)=O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C23H23N5O7S/c24-36(33,34)35-11-14-9-18(22(30)21(14)29)26-19-6-7-25-20-10-17(27-28(19)20)16-3-1-2-12-8-13(23(31)32)4-5-15(12)16/h1-8,10,14,18,21-22,26,29-30H,9,11H2,(H,31,32)(H2,24,33,34)/t14-,18-,21-,22+/m1/s1
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

US Patent


Assay Description
The UAE enzymatic reaction totals 50 μL and contains 50 mmol HEPES (pH 7.5), 0.05% BSA, 2.5 mM MgCl2, 0.1 uM ATP, 8 nM GST-Ubc-2, 35 nM flag-ubi...


US Patent US10202389 (2019)

More data for this
Ligand-Target Pair