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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ubiquitin-like modifier-activating enzyme 1' and Ligand = 'BDBM329909'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ubiquitin-like modifier-activating enzyme 1


(Homo sapiens (Human))
BDBM329909
PNG
((s.e.)-((1R,2R,3S,4R)-4-(2-(2,4-dichloronaphthalen...)
Show SMILES NS(=O)(=O)OC[C@H]1C[C@@H](Nc2ccnc3cc(nn23)-c2c(Cl)cc(Cl)c3ccccc23)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C22H21Cl2N5O5S/c23-14-8-15(24)20(13-4-2-1-3-12(13)14)16-9-19-26-6-5-18(29(19)28-16)27-17-7-11(21(30)22(17)31)10-34-35(25,32)33/h1-6,8-9,11,17,21-22,27,30-31H,7,10H2,(H2,25,32,33)/t11-,17-,21-,22+/m1/s1
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

US Patent


Assay Description
The UAE enzymatic reaction totals 50 μL and contains 50 mmol HEPES (pH 7.5), 0.05% BSA, 2.5 mM MgCl2, 0.1 uM ATP, 8 nM GST-Ubc-2, 35 nM flag-ubi...


US Patent US10202389 (2019)

More data for this
Ligand-Target Pair