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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ubiquitin-like modifier-activating enzyme 1' and Ligand = 'BDBM329917'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ubiquitin-like modifier-activating enzyme 1


(Homo sapiens (Human))
BDBM329917
PNG
((s.e.)-{(1R,2R,3S,4R)-4-[(6-chloro-2-{3-[(trifluor...)
Show SMILES NS(=O)(=O)OC[C@H]1C[C@@H](Nc2c(Cl)cnc3cc(nn23)-c2cccc(SC(F)(F)F)c2)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C19H19ClF3N5O5S2/c20-12-7-25-15-6-13(9-2-1-3-11(4-9)34-19(21,22)23)27-28(15)18(12)26-14-5-10(16(29)17(14)30)8-33-35(24,31)32/h1-4,6-7,10,14,16-17,26,29-30H,5,8H2,(H2,24,31,32)/t10-,14-,16-,17+/m1/s1
PDB
MMDB

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UniProtKB/SwissProt

B.MOAD
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PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

US Patent


Assay Description
The UAE enzymatic reaction totals 50 μL and contains 50 mmol HEPES (pH 7.5), 0.05% BSA, 2.5 mM MgCl2, 0.1 uM ATP, 8 nM GST-Ubc-2, 35 nM flag-ubi...


US Patent US10202389 (2019)

More data for this
Ligand-Target Pair