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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM373517'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM373517
PNG
(FD-2013019 | US9902709, Comparative example 4)
Show SMILES Cn1cc(cn1)-c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)c(Cl)cn1
Show InChI InChI=1S/C23H16Cl2F3N5O2/c1-33-12-13(10-30-33)20-9-21(19(25)11-29-20)35-16-5-2-14(3-6-16)31-22(34)32-15-4-7-18(24)17(8-15)23(26,27)28/h2-12H,1H3,(H2,31,32,34)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.05E+4n/an/an/an/an/an/a



University of Mississippi



Assay Description
Kinase Enzymatic step assay Control (10 μL) Sample Negative Positive Compound 4 μL 4 μL 2.5% 4 μL 2.5% DMSO/kinase DMSO/kinase bu...


J Med Chem 48: 2906-15 (2005)


BindingDB Entry DOI: 10.7270/Q2T43WF5
More data for this
Ligand-Target Pair