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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM373518'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM373518
PNG
(FD-2013017 | US9902709, Comparative example 5)
Show SMILES COc1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)cc(n1)-c1cnn(C)c1
Show InChI InChI=1S/C24H19ClF3N5O3/c1-33-13-14(12-29-33)21-10-18(11-22(32-21)35-2)36-17-6-3-15(4-7-17)30-23(34)31-16-5-8-20(25)19(9-16)24(26,27)28/h3-13H,1-2H3,(H2,30,31,34)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 2.39E+3n/an/an/an/an/an/a



PEKING UNIVERSITY FOUNDER GROUP CO., LTD.

US Patent


Assay Description
Kinase Enzymatic step assay Control (10 μL) Sample Negative Positive Compound 4 μL 4 μL 2.5% 4 μL 2.5% DMSO/kinase DMSO/kinase bu...


US Patent US9902709 (2018)


BindingDB Entry DOI: 10.7270/Q2T43WF5
More data for this
Ligand-Target Pair