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Found 3 Enz. Inhib. hit(s) with Target = 'Vitamin K-dependent protein C' and Ligand = 'BDBM50193243'
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50193243(({(R)-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-2...)
Affinity DataKi:  500nMAssay Description:Competitive inhibition of human APC using S-2366 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50193243(({(R)-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-2...)
Affinity DataIC50:  820nMAssay Description:Inhibition of human aPCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50193243(({(R)-[2-(4-carbamimidoyl-benzylcarbamoyl)-indan-2...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed