Found 3 Enz. Inhib. hit(s) with Target = 'Voltage-dependent T-type calcium channel subunit alpha-1H' and Ligand = 'BDBM50452245' TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Rattus norvegicus)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of Cav3.2 in rat assessed as decrease in calcium flux preincubated for 3 mins followed by CaCl2 addition by Fluo-4-AM dye-based FLIPR assa...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Mus musculus)
Idorsia Pharmaceuticals
Curated by ChEMBL
Idorsia Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of Cav3.2 in mouse assessed as decrease in calcium flux preincubated for 3 mins followed by CaCl2 addition by Fluo-4-AM dye-based FLIPR as...More data for this Ligand-Target Pair
