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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Voltage-gated potassium channel subunit Kv7.1' and Ligand = 'BDBM50106174'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel subunit Kv7.1


(Cavia porcellus)
BDBM50106174
PNG
(CHEMBL332297 | N-(2,2-Dimethyl-cyclohexylmethyl)-4...)
Show SMILES CCCCCCOc1ccc(cc1)C(=O)NCC1CCCCC1(C)C
Show InChI InChI=1S/C22H35NO2/c1-4-5-6-9-16-25-20-13-11-18(12-14-20)21(24)23-17-19-10-7-8-15-22(19,2)3/h11-14,19H,4-10,15-17H2,1-3H3,(H,23,24)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes


J Med Chem 44: 3764-7 (2001)


Article DOI: 10.1021/jm015505u
BindingDB Entry DOI: 10.7270/Q2G1604C
More data for this
Ligand-Target Pair
Voltage-gated potassium channel subunit Kv7.1


(Cavia porcellus)
BDBM50106174
PNG
(CHEMBL332297 | N-(2,2-Dimethyl-cyclohexylmethyl)-4...)
Show SMILES CCCCCCOc1ccc(cc1)C(=O)NCC1CCCCC1(C)C
Show InChI InChI=1S/C22H35NO2/c1-4-5-6-9-16-25-20-13-11-18(12-14-20)21(24)23-17-19-10-7-8-15-22(19,2)3/h11-14,19H,4-10,15-17H2,1-3H3,(H,23,24)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>3.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Bindind affinity value obtained by measuring the displacement of radioligand [3H]-(-)-cytisine from a preparation of whole rat brain


J Med Chem 44: 3764-7 (2001)


Article DOI: 10.1021/jm015505u
BindingDB Entry DOI: 10.7270/Q2G1604C
More data for this
Ligand-Target Pair