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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-gated potassium channel subunit Kv7.1' and Ligand = 'BDBM50279717'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel subunit Kv7.1


(Cavia porcellus)
BDBM50279717
PNG
(1-(2,3-dihydro-6-chlorochromen-4-ylideneamino)-3-(...)
Show SMILES CN1CCN(CCCCn2c(O)cn(N=C3CCOc4ccc(Cl)cc34)c2=O)CC1
Show InChI InChI=1S/C21H28ClN5O3/c1-24-9-11-25(12-10-24)7-2-3-8-26-20(28)15-27(21(26)29)23-18-6-13-30-19-5-4-16(22)14-17(18)19/h4-5,14-15,28H,2-3,6-13H2,1H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 73n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...


Bioorg Med Chem Lett 19: 1477-80 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.022
BindingDB Entry DOI: 10.7270/Q22J6BQK
More data for this
Ligand-Target Pair