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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'bRAF serine/threonine protein kinase' and Ligand = 'BDBM316993'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
bRAF serine/threonine protein kinase


(Homo sapiens (Human))
BDBM316993
PNG
(N-[2,4-Difluoro-3-(4- isopropylamino-7H- pyrrolo[2...)
Show SMILES CC(C)Nc1ncnc2[nH]cc(C(=O)c3c(F)ccc(NS(=O)(=O)c4ccc(cc4)C(C)C)c3F)c12
Show InChI InChI=1S/C25H25F2N5O3S/c1-13(2)15-5-7-16(8-6-15)36(34,35)32-19-10-9-18(26)21(22(19)27)23(33)17-11-28-24-20(17)25(30-12-29-24)31-14(3)4/h5-14,32H,1-4H3,(H2,28,29,30,31)
PDB
MMDB

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PC cid
PC sid
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US Patent
n/an/a<100n/an/an/an/an/an/a



Plexxikon Inc.

US Patent


Assay Description
Assays for biochemical and cell based activity are known in the art, for example, as described in PCT publication WO 2007/002433, the disclosure of w...


US Patent US9617267 (2017)

More data for this
Ligand-Target Pair