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Found 1 hit Enz. Inhib. hit(s) with Target = 'beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ)' and Ligand = 'BDBM31961'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ)


(Helicobacter pylori (Campylobacter pylori))
BDBM31961
PNG
(carbohydrazide derivative, 5d)
Show SMILES Oc1c(Br)cc(C=NNC(=O)c2ccc(Oc3ccccc3)cc2)c(O)c1Br
Show InChI InChI=1S/C20H14Br2N2O4/c21-16-10-13(18(25)17(22)19(16)26)11-23-24-20(27)12-6-8-15(9-7-12)28-14-4-2-1-3-5-14/h1-11,25-26H,(H,24,27)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.28E+4n/an/an/an/an/an/a



Shanghai Institute of Materia Medica



Assay Description
The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...


J Med Chem 52: 2465-81 (2009)


Article DOI: 10.1021/jm8015602
BindingDB Entry DOI: 10.7270/Q2ZK5F1W
More data for this
Ligand-Target Pair