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Found 1 Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM50319185'
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Biotie Therapies

Curated by ChEMBL
LigandPNGBDBM50319185(4-Cyano-1-ethyl-8-methoxy-3-methyl-imidazo[1,5-a]p...)
Affinity DataIC50:  36nMAssay Description:Inhibition of human recombinant PDE10A expressed in baculovirus-SF21 cell system assessed as hydrolysis of [3H]cAMP after 1 hr by liquid scintillatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed