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Found 3 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM135819'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
High Point Pharmaceuticals

US Patent
LigandPNGBDBM135819(US10085990, Example 103 | US10568888, Example 103 ...)
Affinity DataIC50:  17nMAssay Description:A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
High Point Pharmaceuticals

US Patent
LigandPNGBDBM135819(US10085990, Example 103 | US10568888, Example 103 ...)
Affinity DataIC50:  17nMAssay Description:The assay buffer was prepared by diluting 5× supplied Tween-based buffer in 1:5 in water to make 1× buffer. Add desired additive to buffer (DTT or Mn...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
High Point Pharmaceuticals

US Patent
LigandPNGBDBM135819(US10085990, Example 103 | US10568888, Example 103 ...)
Affinity DataIC50:  17nMT: 2°CAssay Description:The assay buffer was prepared by diluting 5× supplied Tween-based buffer in 1:5 in water to make 1× buffer. Add desired additive to buffer (DTT or Mn...More data for this Ligand-Target Pair
In DepthDetails US Patent