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Found 2 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM355750'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM355750(N-Cyclopropyl-3-(3,4-dichlorophenyl)-3H-imidazo[4,...)
Affinity DataIC50:  12.2nMAssay Description:The PDE4B and 4D assays use scintillation proximity assay (SPA) technology to measure the inhibition of human recombinant PDE4B and PDE4D enzyme acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM355750(N-Cyclopropyl-3-(3,4-dichlorophenyl)-3H-imidazo[4,...)
Affinity DataIC50:  630nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed