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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4C' and Ligand = 'BDBM50228823'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4C


(Rattus norvegicus)
BDBM50228823
PNG
(CHEMBL101504)
Show SMILES COc1ccc(cc1OC1CC2C3CCC(C3)C2C1)C1CNC(=O)N1C
Show InChI InChI=1/C21H28N2O3/c1-23-18(11-22-21(23)24)14-5-6-19(25-2)20(8-14)26-15-9-16-12-3-4-13(7-12)17(16)10-15/h5-6,8,12-13,15-18H,3-4,7,9-11H2,1-2H3,(H,22,24)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>100n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]- rolipram binding to rat cerebral cortex membranes


J Med Chem 34: 291-8 (1991)


Article DOI: 10.1021/jm00105a045
BindingDB Entry DOI: 10.7270/Q2NV9MG8
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4C


(Rattus norvegicus)
BDBM50228823
PNG
(CHEMBL101504)
Show SMILES COc1ccc(cc1OC1CC2C3CCC(C3)C2C1)C1CNC(=O)N1C
Show InChI InChI=1/C21H28N2O3/c1-23-18(11-22-21(23)24)14-5-6-19(25-2)20(8-14)26-15-9-16-12-3-4-13(7-12)17(16)10-15/h5-6,8,12-13,15-18H,3-4,7,9-11H2,1-2H3,(H,22,24)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of calcium-independent Phosphodiesterase 4


J Med Chem 34: 291-8 (1991)


Article DOI: 10.1021/jm00105a045
BindingDB Entry DOI: 10.7270/Q2NV9MG8
More data for this
Ligand-Target Pair