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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4C' and Ligand = 'BDBM50228830'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4C


(Rattus norvegicus)
BDBM50228830
PNG
(CHEMBL101505)
Show SMILES COc1ccc(cc1OC1CC2CCC(C2)C1)C1CNC(=O)N1C
Show InChI InChI=1/C19H26N2O3/c1-21-16(11-20-19(21)22)14-5-6-17(23-2)18(10-14)24-15-8-12-3-4-13(7-12)9-15/h5-6,10,12-13,15-16H,3-4,7-9,11H2,1-2H3,(H,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>100n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]- rolipram binding to rat cerebral cortex membranes


J Med Chem 34: 291-8 (1991)


Article DOI: 10.1021/jm00105a045
BindingDB Entry DOI: 10.7270/Q2NV9MG8
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4C


(Rattus norvegicus)
BDBM50228830
PNG
(CHEMBL101505)
Show SMILES COc1ccc(cc1OC1CC2CCC(C2)C1)C1CNC(=O)N1C
Show InChI InChI=1/C19H26N2O3/c1-21-16(11-20-19(21)22)14-5-6-17(23-2)18(10-14)24-15-8-12-3-4-13(7-12)9-15/h5-6,10,12-13,15-16H,3-4,7-9,11H2,1-2H3,(H,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.40E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of calcium-independent Phosphodiesterase 4


J Med Chem 34: 291-8 (1991)


Article DOI: 10.1021/jm00105a045
BindingDB Entry DOI: 10.7270/Q2NV9MG8
More data for this
Ligand-Target Pair