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Found 2 Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM204627'
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Oslo University Hospital

US Patent
LigandPNGBDBM204627(1-(5-butoxy-2-chloro-phenyl)-4-methyl-[1,2,4]triaz...)
Affinity DataIC50:  3nMAssay Description:Isolated cardiomyocytes were washed twice in PBS at room temperature, transferred to 4% paraformaldehyde (PFA) and gently shaken for 30 min, then was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Oslo University Hospital

US Patent
LigandPNGBDBM204627(1-(5-butoxy-2-chloro-phenyl)-4-methyl-[1,2,4]triaz...)
Affinity DataIC50:  3nMAssay Description:The DNA encoding PDE2A (NM002599) was cloned and the gene was inserted in the baculovirus and the enzyme-protein expressed in SF21-cells. The enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent