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Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM204640'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cGMP-dependent 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM204640
PNG
(4-chloro-3-(4-methyl-[1,2,4]triazolo[4,3-a]quinoxa...)
Show SMILES Cc1nc2ccccc2n2c(nnc12)-c1cc(O)ccc1Cl
Show InChI InChI=1S/C16H11ClN4O/c1-9-15-19-20-16(11-8-10(22)6-7-12(11)17)21(15)14-5-3-2-4-13(14)18-9/h2-8,22H,1H3
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The DNA encoding PDE2A (NM002599) was cloned and the gene was inserted in the baculovirus and the enzyme-protein expressed in SF21-cells. The enzyme ...


US Patent US9540379 (2017)


BindingDB Entry DOI: 10.7270/Q2RB72SP
More data for this
Ligand-Target Pair