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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50300955'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM50300955
PNG
(3-(2-(dimethylamino)ethylamino)-7-(6-methoxypyridi...)
Show SMILES CCCOCCn1c2cc(ncc2nc(NCCN(C)C)c1=O)-c1ccc(OC)nc1
Show InChI InChI=1S/C22H30N6O3/c1-5-11-31-12-10-28-19-13-17(16-6-7-20(30-4)25-14-16)24-15-18(19)26-21(22(28)29)23-8-9-27(2)3/h6-7,13-15H,5,8-12H2,1-4H3,(H,23,26)
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Similars

Article
PubMed
n/an/a 0.780n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of PDE5


Bioorg Med Chem Lett 19: 5209-13 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.019
BindingDB Entry DOI: 10.7270/Q2H41RHV
More data for this
Ligand-Target Pair